According to UK Guardian, the number is the highest ever in a single flight.
The move comes barely 48 hours after Keir Starmer, UK prime minister, agreed a deal to deport migrants arriving in the Chagos Islands in small boats to St Helena, a British island territory more than 5,000 miles away in the Atlantic Ocean.
The Home Office told the UK Guardian on Friday that the deportations were part of a “major surge” in immigration enforcement and returns.
Since Starmer came to power in July, 3,600 people have been returned to various countries, including about 200 to Brazil and 46 to Vietnam and Timor-Leste.
There are also regular deportation flights to Albania, Lithuania and Romania.
However, deportation flights to Nigeria and Ghana are relatively rare, with just four recorded since 2020.
The number rose in June after some 13 Nigerians were flown to Lagos from the UK.
One of the Nigerian deportees in the latest removal said he was trafficked.
“I told the Home Office I was a victim of trafficking. They rejected my claim,” he told the Guardian.
Another said he had been in the UK for 15 years as an asylum seeker and had no criminal record but the Home Office refused his claim.
In August, Nigeria reportedly signed a deportation agreement with the UK, which would see the arrival of illegal immigrants in the country.
The partnership came into effect after an asylum deal with Rwanda turned sour.